Welcome to the Integrated Research Application System (IRAS)


IRAS Queries Line will be closed from 5pm on Tuesday 23 December 2014 until 9am on Monday 5 January 2015 when normal service will resume.

IRAS Technical Helpdesk will be closed from 3pm on Wednesday 24 December until 10.30am on Monday 29 December and from 3pm on Wednesday 31 December until 9am on Friday 2 January 2015 when normal service will resume. Please note that on there will be a reduced service available between 1-3pm on 24 December and on 29, 30 and 31 December the Technical Helpdesk will only be open between 10.30am and 3pm and with a reduced service.

30 September 2014: Terms of the Sponsor declaration have been updated to include a statement that clinical trials have been registered. More information on this change is provided in Updates.

19 May 2014: REC and non-NHS SSI forms are now electronically submitted.
This change accompanies other changes to the REC application process, including how applications are booked. Please refer to the HRA website and Updates page for more information.

28 April 2014: Electronic authorisation has become mandatory for declarations in some forms from today.
Click here for more information.

The Integrated Research Application System (IRAS):
  • Is a single system for applying for the permissions and approvals for health and social care / community care research in the UK
  • Enables you to enter the information about your project once instead of duplicating information in separate application forms
  • Uses filters to ensure that the data collected and collated is appropriate to the type of study, and consequently the permissions and approvals required
  • Helps you to meet regulatory and governance requirements
IRAS captures the information needed for the relevant approvals from the following review bodies:
  • Administration of Radioactive Substances Advisory Committee (ARSAC)
  • Gene Therapy Advisory Committee (GTAC)
  • Medicines and Healthcare products Regulatory Agency (MHRA)
  • NHS / HSC R&D offices
  • NRES/ NHS / HSC Research Ethics Committees
  • Confidentiality Advisory Group (CAG), formerly the National Information Governance Board (NIGB)
  • National Offender Management Service (NOMS)
  • Social Care Research Ethics Committee
Please help us to improve IRAS by sending your feedback to iras.queries@nhs.net. Your comments and suggestions will be included in the next review of the system.
Please Login

First time and new users please click here.

  (Your full e-mail address)

Forgotten Password? Click here

* Passwords are case sensitive.

Quick Links
 Getting started

The Integrated Research Application System uses .pdf files to print. You need to have the free Adobe PDF Reader installed on your computer.
Click here to download the Adobe Reader

If you have difficulty installing this software please contact your computer administrator.

IRAS Integrated Research Application System, version 3.5.3, 26/10/2014, IRAS Dataset version 3.5.
The Health Research Authority (HRA) acknowledges the Integrated Research Application System (IRAS) partners in developing IRAS content. © Health Research Authority 2014.
Copyright and other intellectual property rights in the content of the Integrated Research Application System (IRAS) belong to the HRA and all rights are reserved. Terms & Conditions, Privacy Policy.