Advice on completing and submitting applications
Please contact the relevant source of advice for each type of application.
1. Research Ethics Committee (REC)
For advice on the REC application process, please go to http://www.hra.nhs.uk/research-community/applying-for-approvals/research-ethics-committee/ or phone the REC Manager of your local/chosen REC. Contact details for all RECs in the UK are available at http://www.hra.nhs.uk/resources/applying-to-recs/nhs-rec-directory/.
If you cannot obtain the answer to your question, please contact firstname.lastname@example.org.
2. NHS management permission ("R&D approval")
For all enquiries relating to the NIHR Co-ordinated System for gaining NHS Permissions (NIHR CSP) in England, please contact the CSP Helpdesk at email@example.com. Further information is available via the NIHR website. Note: From 31 March 2016 all applications to conduct research in the NHS in England come under HRA Approval. Please refer to the NIHR website for information about how this affects Portfolio studies and refer to IRAS guidance for HRA Approval.
For further guidance on seeking HSC R&D Permission for participating HSC organisations in Northern Ireland please refer to the HSC website.
For all enquiries relating to the multicentre R&D review in Scotland through NHS Research Scotland (NRS), please contact the Coordinating Unit at NHSG.NRSPCC@nhs.net. Further information is available from the NHS Research Scotland Permissions Coordinating Centre (NRS Permission CC) website. For all enquiries related to single-centre research in Scotland you should contact the local R&D office. For further guidance on seeking NHS R&D Permission in Scotland please refer to the NHS Research Scotland website.
For all enquiries related to gaining research permissions from NHS organisations in Wales please contact the Health and Care Research Wales Permissions Service at: Researchfirstname.lastname@example.org. For further guidance on seeking NHS R&D Permission in Wales please refer to the Health and Care Research Wales website.
For all other enquiries about applying to conduct research in NHS/HSC organisations anywhere in the UK, please contact your local NHS/HSC R&D office. Contact details and further information are available on the NHS R&D Forum website.
3. Gene Therapy Advisory Committee (GTAC) applications
For advice on all gene therapy applications, please refer to: http://www.hra.nhs.uk/resources/applying-to-recs/gene-therapy-advisory-committee-gtac/
4. Confidentiality Advisory Group (CAG) applications
The Health Research Authority (HRA) is responsible for the review function under Section 251 of the NHS Act 2006 . The HRA has established the Confidentiality Advisory Group (CAG) to review applications and provide advice to the HRA in respect of this function. Please refer to http://www.hra.nhs.uk/about-the-hra/our-committees/section-251/ for more information. Guidance on applications under Section 251 of the NHS Act 2006 is provided at http://www.hra.nhs.uk/research-community/applying-for-approvals/confidentiality-advisory-group-cag/ .
To contact the Confidentiality Advisory Group email: email@example.com or phone 020 7972 2557
5. Medicines and Healthcare products Regulatory Agency (MHRA) Medicines
For applications for authorisation of clinical trials of investigational medicinal products, please refer to the guidance on the MHRA website at: https://www.gov.uk/guidance/clinical-trials-for-medicines-apply-for-authorisation-in-the-uk.
Further advice on particular submissions may be sought from the Clinical Trials Unit at MHRA by emailing firstname.lastname@example.org
6. Medicines and Healthcare products Regulatory Agency (MHRA) Devices Division
For advice on the regulation of medical devices in the UK and for applications for Notice of No Objection in the case of clinical investigations of medical devices conducted by manufacturers, please contact the MHRA Devices Division. Contact details and further guidance are available at: https://www.gov.uk/guidance/notify-mhra-about-a-clinical-investigation-for-a-medical-device.
7. Administration of Radioactive Substances Advisory Committee (ARSAC)
ARSAC applications are required from nuclear medicine professionals at each site to administer radioactive exposures in research that would be additional to normal care at the site. Further guidance is available at https://www.gov.uk/government/organisations/administration-of-radioactive-substances-advisory-committee. The ARSAC Support Unit may be contacted via email at: ARSAC@phe.gov.uk or by writing to ARSAC Support Unit, Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Chilton, Didcot, Oxfordshire, OX11 0RQ
8. Her Majesty's Prison and Probation Service (HMPPS)
For advice on the research application process within HMPPS please see:
https://www.gov.uk/government/organisations/her-majestys-prison-and-probation-service/about/research ; and
For further guidance and assistance please contact the National Research Coordinator at National.Research@noms.gsi.gov.uk
9. Health Research Authority (HRA)
For guidance on applying for HRA Approval, please go to the IRAS Help page and/or the HRA website. If your question is not answered by this guidance, please contact the HRA Approval team (email: email@example.com)
For general queries on functionality and to provide feedback on IRAS
Please email us at firstname.lastname@example.org if you have any general queries about the system or its functionality. Please also use this email address if you would like to provide feedback on IRAS.
If you require help with the technical aspects of using IRAS, please contact the IRAS Technical Helpdesk on 0207 043 0734 or email them at email@example.com. The IT Help Desk operates (9am to 5pm excluding holidays and weekends).