CHRISTMAS/NEW YEAR: Please note that the:
IRAS Queries Line will be closed from 5pm on Thursday 22 December 2016 until 9am on Tuesday 3 January 2017.
IRAS Technical Helpdesk will be available between 10.30am – 3pm on Friday 23 December and then closed until 9am on Wednesday 28 December. On 28 and 29 December the Helpdesk will be available 9am – 5pm but on Friday 30 December the service will only be open between 10.30am – 3pm. The Helpdesk will then be closed until 9am on Tuesday 3 January 2017.

7 September 2016: IRAS updated to v5.3.2. This version includes removal of the function to create new minimal dataset projects, addition of a field to the non-CTIMP Notice of Substantial Amendment form, a new question in the project filter and functionality for creation of ARSAC site forms in projects seeking HRA Approval. This version also includes some minor updates to embedded guidance and some maintenance updates. Applicants are recommended to refer to the Updates page for more information.

7 June 2016: IRAS updated to v5.3.1. This version is primarily a maintenance release; however it also includes some minor updates to embedded guidance, removal of question A6-3 and an update affecting ARSAC applications. Applicants are recommended to refer to the Updates page for more information.

20 May 2016: IRAS e-learning module updated. The revised module, which is free to use and provides an overview of the functionality in IRAS, can be accessed via the horizontal toolbar at the top of this page.


The Integrated Research Application System (IRAS):
  • Is a single system for applying for the permissions and approvals for health and social care / community care research in the UK
  • Enables you to enter the information about your project once instead of duplicating information in separate application forms
  • Uses filters to ensure that the data collected and collated is appropriate to the type of study, and consequently the permissions and approvals required
  • Helps you to meet regulatory and governance requirements
IRAS captures the information needed for the relevant approvals from the following review bodies:
  • Administration of Radioactive Substances Advisory Committee (ARSAC)
  • Confidentiality Advisory Group (CAG)
  • Gene Therapy Advisory Committee (GTAC)
  • Health Research Authority (HRA) for projects seeking HRA Approval
  • Medicines and Healthcare products Regulatory Agency (MHRA)
  • NHS / HSC R&D offices
  • NHS / HSC Research Ethics Committees
  • National Offender Management Service (NOMS)
  • Social Care Research Ethics Committee
Please help us to improve IRAS by sending your feedback to iras.queries@nhs.net. Your comments and suggestions will be included in the next review of the system.
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IRAS Integrated Research Application System, version 5.3.2, 07/09/2016, IRAS Dataset version 3.5.
The Health Research Authority (HRA) acknowledges the Integrated Research Application System (IRAS) partners in developing IRAS content. © Health Research Authority 2016.
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