IMPORTANT: Advance notice of essential maintenance work scheduled for Wednesday 22 May – information for users about expected system availability. 
IRAS will not be available to users from 19.00 to 23.00 BST Wednesday 22 May 2019 while essential system maintenance work is carried out.

IMPORTANT: Information for applicants with NHS sites in Wales.
On 16 April 2018 Health and Care Research Wales implemented an interim step to align its processes and paperwork so that there is consistency across England and Wales for researchers. As part of this change, researchers starting new applications in IRAS no longer use NHS Site Specific Information (SSI) forms for NHS sites in Wales. See the Health and Care Research Wales website for further details. 

IMPORTANT: Information for applicants to ARSAC.
On 6 February 2018 the Administration of Radioactive Substances Advisory Committee (ARSAC) changed the way it grants approvals for research. Please refer to ARSAC website for details 

19 February 2019: IRAS updated to v5.11. This version update enables electronic submission of the application to MHRA Devices for clinical investigations of medical devices. Applicants should to refer to the Updates page for more information about this version release.

 13 December 2018: IRAS updated to v5.10. This update is a maintenance release that includes some updates to reference data and minor edits of embedded text. Please refer to the Updates page for more information.

23 July 2018: IRAS Privacy Policy statement updated. To review the current statement, please click on Privacy Policy

28 June 2018: IRAS updated to v5.9.
This version update enables single electronic submission of the IRAS Form for all research conducted in NHS/HSC that is led from Northern Ireland, Scotland or Wales. This release also includes some minor updates to on screen guidance and an update of NHS/HSC organisation codes in Part C. Applicants should to refer to the Updates page for more information about how this version release.

The Integrated Research Application System (IRAS):
  • Is a single system for applying for the permissions and approvals for health and social care / community care research in the UK
  • Enables you to enter the information about your project once instead of duplicating information in separate application forms
  • Uses filters to ensure that the data collected and collated is appropriate to the type of study, and consequently the permissions and approvals required
  • Helps you to meet regulatory and governance requirements
IRAS captures the information needed for the relevant approvals from the following review bodies:
  • Administration of Radioactive Substances Advisory Committee (ARSAC)
  • Confidentiality Advisory Group (CAG)
  • Gene Therapy Advisory Committee (GTAC)
  • Health Research Authority (HRA) for projects seeking HRA Approval
  • Medicines and Healthcare products Regulatory Agency (MHRA)
  • NHS / HSC R&D offices
  • NHS / HSC Research Ethics Committees
  • Her Majesty's Prison and Probation Service (HMPPS)
  • Social Care Research Ethics Committee
Please help us to improve IRAS by sending your feedback to iras.queries@nhs.net. Your comments and suggestions will be included in the next review of the system.
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IRAS Integrated Research Application System, version 5.11, 19/02/2019, IRAS Dataset version 3.5.
The Health Research Authority (HRA) acknowledges the Integrated Research Application System (IRAS) partners in developing IRAS content. © Health Research Authority 2019.
Copyright and other intellectual property rights in the content of the Integrated Research Application System (IRAS) belong to the HRA and all rights are reserved. Terms & Conditions, Privacy Policy.